online

Wednesdays, 14:00-15:30

EXAM: Thursday, the 19th of January 2023, at 10:15, INF 306 "Theoretikum", Ground floor, SR13

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Wednesdays 14:00-15:30, lectures online, 7 lecture units

First lecture: 26. Oct. 2022, then the following lectures on: 2. Nov., 9. Nov., 16. Nov., 23. Nov., 30. Nov. and 7. Dec, (eventual backup date 14. Dec.2022)

the lecture slides will be available for download shortly before the respective lecture.

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To join the lecture as a Zoom meeting, please click on the following link:

https://us02web.zoom.us/j/84205962071?pwd=Y2VSL0RaOC90bllqeEZrM3N3YmExdz09

This interdisciplinary course on the interface of organic chemistry, chemical, molecular and synthetic biology aims to provide the current status of research on the following topics:

Artificial genetic polymers and oligonucleotide analogues; unnatural base pairing – expansion of the genetic alphabet;

artificial ribozymes for efficient catalysis and recognition (SELEX, DNAzymes, foldamers);

biosynthetic incorporation of unnatural aminoacids (UAAs) into proteins;

protein engineering – production of enzymes with unknown or unnatural properties, ab initio protein design, directed evolution, theozymes;

Artificial lipid vesicles as models for protocell multiplication;

This lecture will be continued in SoSe2023 as a course "The molecular origins of life", focused on processes which could allow abiotic generation of biomolecules (aminoacids, lipids, nucleotides, sugars) on the early Earth for the following origin of life.