EXAM: Wednesday, the 17th of January 2024, at 17:00, INF 252 (Hörsaalzentrum Chemie), Ground floor, Hörsaal Ost (HSO) - https://www.uni-heidelberg.de/fakultaeten/chemgeo/aktuelles/LageplanINF252.html

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Hybrid-Lecture (in person + online)

Wednesdays 14:00-15:30, Seminar Room SR 201, Geb. 30.42 (Organische Chemie), 2. OG., 7 lecture units

First lecture: 25. Oct. 2023, then the following lectures on: 8. Nov., 15. Nov., 22. Nov., 29. Nov., 6. Dec and 13. Dec, (eventual backup date 20. Dec.2022)

the lecture slides will be available for download shortly before the respective lecture.

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To join the lecture as a Zoom meeting, please click on the following link:

https://us02web.zoom.us/j/89079835848?pwd=MU83ZXlqa2RWNlFzVXhvNzBocDlGQT09

Meeting ID: 890 7983 5848
Access code: 443707

This interdisciplinary course on the interface of organic chemistry, chemical, molecular and synthetic biology aims to provide the current status of research on the following topics:

Artificial genetic polymers and oligonucleotide analogues; unnatural base pairing – expansion of the genetic alphabet;

artificial ribozymes for efficient catalysis and recognition (SELEX, DNAzymes, foldamers);

biosynthetic incorporation of unnatural aminoacids (UAAs) into proteins;

protein engineering – production of enzymes with unknown or unnatural properties, ab initio protein design, directed evolution, theozymes;

Artificial lipid vesicles as models for protocell multiplication;

This lecture will be continued in SoSe2024 as a course "The molecular origins of life", focused on processes which could allow abiotic generation of biomolecules (aminoacids, lipids, nucleotides, sugars) on the early Earth for the following origin of life.